Name: High Protein Chicken Parmesan Casserole
Prep time: 10 min
Cook time: 35 min
Total time: 45 min
Cuisine: Italian
Ingredients: 4 boneless, skinless chicken breasts; 1 cup whole wheat breadcrumbs; 1/2 cup grated Parmesan cheese; 2 cups marinara sauce; 1 cup shredded mozzarella cheese; 2 tbsp olive oil; 1 tsp garlic powder; 1 tsp dried oregano; Fresh basil for garnish

Jump to Recipe·Print Recipe

🍽️ Delicious & Protein-Packed: High Protein Chicken Parmesan Casserole

1. Introduction

If you’re craving a hearty, satisfying dish that is both rich in flavor and packed with protein, then the high protein chicken parmesan casserole is your new best friend. This wholesome twist on classic chicken parmesan combines crispy breaded chicken, zesty marinara, and gooey cheese into a warm, comforting bake. Designed for those seeking a deliciously healthy chicken casserole, this recipe hits all the right notes—texture, taste, and nutrition—making it perfect for weeknight dinners or meal prep.

2. Why You’ll Love This Recipe

Ready in 40 minutes: Quick enough for busy weeknights without sacrificing flavor.
High in protein: Loaded with hearty chicken and cheese, ideal for muscle building and satiety.

One-pan comfort: Minimal dishes, maximum flavor, thanks to layered ingredients baked to perfection.
Customizable: Versatile for dietary tweaks like low-carb or gluten-free modifications.

3. Ingredient Notes

For this healthy chicken casserole, quality matters. Use high-protein chicken breast for lean muscle and a tender bite. Opt for Italian-seasoned breadcrumbs to amplify flavor, or make your own by blending whole-grain bread with dried herbs. When selecting cheese, mozzarella offers that signature melt, while Parmesan adds a savory punch. Using fresh garlic and aromatic herbs like basil elevates the dish’s flavor profile, so don’t cut corners on freshness.

4. Kitchen Tools You Need

To achieve perfect results, certain kitchen gadgets are indispensable. For example, this Compact 6-in-1 Digital Air Fryer can be used to crisp the chicken before baking for an irresistible crunch. The T-fal 14-Piece Hard Anodized Nonstick Cookware Set ensures even cooking and easy cleanup. Preparing this casserole is seamless with reliable tools like these by your side, making the process more enjoyable and efficient.

5. How to Make High Protein Chicken Parmesan Casserole

Preparation of Chicken

Start by preheating your oven to 375°F (190°C). Flatten chicken breasts to an even thickness for uniform cooking—this is critical for crispy edges. Season well with salt, pepper, and Italian herbs. Dredge the chicken in beaten eggs, then coat generously with seasoned breadcrumbs. For extra crunch, you can add grated Parmesan to your breadcrumb mixture.

Sear the breaded chicken in a hot skillet with a splash of olive oil until golden and crispy on both sides—that’s your aroma filling the kitchen! It should look beautifully browned, with a fragrant smell that promises delicious bites ahead.

Assembling the Casserole

Place the crispy chicken in a baking dish. Cover with your marinara sauce—rich and slightly chunky, with aromatic garlic and basil. Sprinkle generous amounts of shredded mozzarella and Parmesan cheese over the top for that gooey, cheesy finish. Bake uncovered for about 20-25 minutes until bubbling and cheese is perfectly melted and golden.

Watch for the cheese to turn bubbly and slightly browned—this visual cue signals it’s ready to serve. Your kitchen will be filled with a comforting aroma that beckons everyone to the table!

6. Expert Tips for Success

Use a shallow baking dish: Ensures even heat distribution and crispy edges on the chicken.

Drain excess marinara: Too much sauce can make the casserole watery; use a thick, flavorful sauce instead.
Precook the chicken: Searing pre-cooked chicken helps maintain crispy texture and prevents overcooking during baking.
Cheese coverage: Cover the top to prevent burning but uncover for the last few minutes to achieve perfect browning.

7. Variations & Substitutions

Adapt this recipe based on preferences. For lower carbs, swap breadcrumbs with crushed almonds or omit breading altogether. Use gluten-free breadcrumb options for a gluten-sensitive version. For plant-based eaters, substitute chicken with tofu or tempeh, and use vegan cheese to keep it dairy-free.

8. Storage & Reheating

This casserole keeps well in an airtight container in the refrigerator for up to 4 days. To reheat, use a microwave or oven until warmed through, and consider adding a sprinkle of fresh cheese or herbs to refresh the flavors. For extra convenience, turn leftovers into a quick pasta bake or serve on a bed of greens for a lighter option.

9. FAQ

Can I make this casserole ahead of time?

Absolutely! Assemble the casserole, cover, and refrigerate for up to 24 hours. Bake when ready, adding a few extra minutes to your cooking time.

Is this dish suitable for meal prep?

Yes, this healthy chicken casserole is ideal for meal prep. Divide into individual portions and store in airtight containers for easy grab-and-go meals.

Can I freeze leftovers?

Yes, pack leftovers in freezer-safe containers. Thaw overnight and reheat thoroughly for a delicious next-day meal.

10. Conclusion

In just under an hour, you can create a satisfying, protein-rich chicken parmesan casserole that combines crispy, cheesy indulgence with wholesome ingredients. This dish not only satisfies your taste buds but also fuels your body with high-quality protein. Give it a try, and enjoy the comforting flavors of this crowd-pleasing casserole—a perfect balance of health and comfort!

High Protein Chicken Parmesan Casserole